Validating a Minimally Invasive Tissue Sampling Technique as a New Paradigm for Determining Cause of Death: Experience from Kazakhstan
- Matthew Naanlep Tanko
- Nazarbayev University Astana
- Republic of Kazakhstan
- To determine the acceptability of MITS over CDA in among our study population
- To compare the diagnostic accuracy, classification and assignment of cause of death between MITs and CDA
- Children < 10 months
Determining Efficiently the Cause of Death among Adults and Generating Mortality Evidence at MITS Alliance Unit Nepal (DECODE MAUN); NEPAL
- Nuwadatta Subedi
- Gandaki Medical College
- What are the causes of non-violent deaths in study population as determined by standard autopsy procedure?
- What are the causes of deaths in study population as determined by the MITS technique?
- In what percentage of cases of non-violent deaths does MITS technique provide conclusive cause of death in Nepalese adults?
- All ages
Minimally Invasive Tissue Sampling for TBM in Zambia (MITZ study)
- Omar K. Siddiqi
- University of Zambia School of Medicine
- Establish prevalence of TB meningitis (TBM) among deceased Zambian adults who initially presented as meningoencephalitis.
Minimally Invasive Tissue Sampling (MITS) Implementation at Kigali University Teaching Hospital (CHUK)
- Ntakirutimana Gervais
- University Teaching Hospital of Kigali (CHUK)
- To determine the perception of MITS by health care providers and community
- To determine the major causes of death in Rwanda
- One hundred (100) bodies of any age group from any health facility, families and communities on the territory of Rwanda will be enrolled in the MITS program.
- All ages
Study of MITS in Neonates, Ethiopia
- Rahell Hailu
- Addis Ababa University
- Evaluate the capability of MITS for identification of cause of death in neonates.
- Identify major diagnostic categories that could be made on MITS samples,
- Assess sampling yield and draw up adequacy criteria for each sampled organ, and test the accuracy of imaging guided samples from the brain and intestine,
- Assess the sampling yield of samples collected by low level health professionals(nurses and health officers)
Effectiveness Of MITS In Establishing The Cause Of Death After A Short Duration Tertiary Hospitalization In Tanzania (EMECaD)
- Alex Mremi
- Kilimanjaro Christian Medical Centre
- To determine causes of deaths in short duration hospitalized patients at KCMC, a tertiary hospital in Northern Tanzania.
- To assess the accuracy of clinical diagnosis and of MITS compared to CDA (gold standard) in determining the cause of death.
- To assess the barriers, knowledge, attitudes, and perceptions of families of the deceased towards autopsy
Validity of minimally invasive tissue sampling in determining the cause of death in stillbirths and neonates due to neurological insults in the brain: A study in a tertiary care center in India
- Mary Mathew
- Kasturba Medical College
- Identify the causes and etiologies associated with neurological insults in the brain resulting in stillbirths and neonatal deaths using the MITS apprach
- Study the patterns of brain injury in preterm versus term infants with special reference to white matter injury
MITS at community and hospital Facilities: Melghat, India
- Ashish Satav
- MAHAN trust
- To identify accurately the causes of deaths (0-5 years and 16 to 60 years age group and still births) in 4 Govt. hospitals; 1 MAHAN base hospital & in community, 93 villages with population of 101792 of rural- tribal Melghat, Central India over one year.
- Children < 5
- Adults 16-60
Promoting MITS activities to determine cause of death among neonates and stillbirths in tertiary care teaching hospital
- Dhaded Sangappa
- J N Medical College Belagavi
- To integrate MITS in identifying cause of neonatal deaths and stillbirths in tertiary care teaching hospital setting.
- To know the effect of hypertensive disorders of pregnancy, preterm birth, asphyxia and infection on placenta and tissues like Lungs, Liver and Brain.
- To know the effect of Pre-eclampsia, prematurity, asphyxia and infection on placenta and tissues like Lungs, Liver and Brain.
- Neonatal deaths
Utility of Minimally Invasive Autopsy in improvement of causes of death classification in Rwanda
- Djibril Mbarushimana
- University Teaching Hospital Of Butare Rwanda
- Increase reporting of in hospital death,
- Classify causes of death accurately,
- Identify gaps for strengthening of anatomical pathology laboratory,
- Contribute to initiation of medical autopsy rotation site for pathology residents and medical students.
- Children > 28d - adult
Neonatal in-hospital cause of death determination by minimal invasive tissue sampling technique in a low-income region of Argentina.
- Mauricio T. Caballero
- Fundación INFANT
- To determine the burden of asphyxia and respiratory and central nervous system infectious diseases as COD in neonates hospitalized in our hospital Network.
- To identify demographic and clinical factors associated with neonatal in-hospital deaths.
- To explore family and physician acceptance of MITS as a routine procedure after in-hospital neonatal death
Using MITS to calibrate adjudicated respiratory vs. non-respiratory deaths among young Zambian infants
- Christopher Gill
- University Teaching Hospital
- To assess the feasibility and acceptability of MITS sampling in this population
- To use MITS to calibrate our existing process for adjudicating infant deaths as 'Respiratory' vs. 'Non-Respiratory'
- To use MITS to establish the rate of PCR concordance between upper and lower respiratory tract RSV infections
- Infants 4d - 6m