Grantees


Kazakhstan

Validating a Minimally Invasive Tissue Sampling Technique as a New Paradigm for Determining Cause of Death: Experience from Kazakhstan

  • Matthew Naanlep Tanko
  • Nazarbayev University Astana
  • Republic of Kazakhstan
Objectives
  • To determine the acceptability of MITS over CDA in among our study population
  • To compare the diagnostic accuracy, classification and assignment of cause of death between MITs and CDA
Target Population
  • Children < 10 months

Team behind DECODE MAUN

Determining Efficiently the Cause of Death among Adults and Generating Mortality Evidence at MITS Alliance Unit Nepal (DECODE MAUN); NEPAL

  • Nuwadatta Subedi
  • Gandaki Medical College
  • Nepal
Objectives
  • What are the causes of non-violent deaths in study population as determined by standard autopsy procedure?
  • What are the causes of deaths in study population as determined by the MITS technique?
  • In what percentage of cases of non-violent deaths does MITS technique provide conclusive cause of death in Nepalese adults?
Target Population
  • All ages

Team behind MITZ study

Minimally Invasive Tissue Sampling for TBM in Zambia (MITZ study)

  • Omar K. Siddiqi
  • University of Zambia School of Medicine
  • Zambia
Objectives
  • Establish prevalence of TB meningitis (TBM) among deceased Zambian adults who initially presented as meningoencephalitis.
Target Population
  • Adults

Team behind MITS implementation at Kigali

Minimally Invasive Tissue Sampling (MITS) Implementation at Kigali University Teaching Hospital (CHUK)

  • Ntakirutimana Gervais
  • University Teaching Hospital of Kigali (CHUK)
  • Rwanda
Objectives
  • To determine the perception of MITS by health care providers and community
  • To determine the major causes of death in Rwanda
  • One hundred (100) bodies of any age group from any health facility, families and communities on the territory of Rwanda will be enrolled in the MITS program.
Target Population
  • All ages

Ethiopia

Study of MITS in Neonates, Ethiopia

  • Rahell Hailu
  • Addis Ababa University
  • Ethiopia
Objectives
  • Evaluate the capability of MITS for identification of cause of death in neonates.
  • Identify major diagnostic categories that could be made on MITS samples,
  • Assess sampling yield and draw up adequacy criteria for each sampled organ, and test the accuracy of imaging guided samples from the brain and intestine,
  • Assess the sampling yield of samples collected by low level health professionals(nurses and health officers)
Target Population
  • Neonates

Team behind EMECaD

Effectiveness Of MITS In Establishing The Cause Of Death After A Short Duration Tertiary Hospitalization In Tanzania (EMECaD)

  • Alex Mremi
  • Kilimanjaro Christian Medical Centre
  • Tanzania
Objectives
  • To determine causes of deaths in short duration hospitalized patients at KCMC, a tertiary hospital in Northern Tanzania.
  • To assess the accuracy of clinical diagnosis and of MITS compared to CDA (gold standard) in determining the cause of death.
  • To assess the barriers, knowledge, attitudes, and perceptions of families of the deceased towards autopsy
Target Population
  • Adults
  • Children

Kasturba Medical College Team

Validity of minimally invasive tissue sampling in determining the cause of death in stillbirths and neonates due to neurological insults in the brain: A study in a tertiary care center in India

  • Mary Mathew
  • Kasturba Medical College
  • India
Objectives
  • Identify the causes and etiologies associated with neurological insults in the brain resulting in stillbirths and neonatal deaths using the MITS apprach
  • Study the patterns of brain injury in preterm versus term infants with special reference to white matter injury
Target Population
  • Neonates
  • Stillbirths

Team behind MITS at community and hospital Facilities

MITS at community and hospital Facilities: Melghat, India

  • Ashish Satav
  • MAHAN trust
  • India
Objectives
  • To identify accurately the causes of deaths (0-5 years and 16 to 60 years age group and still births) in 4 Govt. hospitals; 1 MAHAN base hospital & in community, 93 villages with population of 101792 of rural- tribal Melghat, Central India over one year.
Target Population
  • Neonates
  • Children < 5
  • Adults 16-60

JNM

Promoting MITS activities to determine cause of death among neonates and stillbirths in tertiary care teaching hospital

  • Dhaded Sangappa
  • J N Medical College Belagavi
  • India
Objectives
  • To integrate MITS in identifying cause of neonatal deaths and stillbirths in tertiary care teaching hospital setting.
  • To know the effect of hypertensive disorders of pregnancy, preterm birth, asphyxia and infection on placenta and tissues like Lungs, Liver and Brain.
  • To know the effect of Pre-eclampsia, prematurity, asphyxia and infection on placenta and tissues like Lungs, Liver and Brain.
Target Population
  • Stillbirths
  • Neonatal deaths

Team behind Utility of Minimally Invasive Autopsy in improvement of causes of death classification

Utility of Minimally Invasive Autopsy in improvement of causes of death classification in Rwanda

  • Djibril Mbarushimana
  • University Teaching Hospital Of Butare Rwanda
  • Rwanda
Objectives
  • Increase reporting of in hospital death,
  • Classify causes of death accurately,
  • Identify gaps for strengthening of anatomical pathology laboratory,
  • Contribute to initiation of medical autopsy rotation site for pathology residents and medical students.
Target Population
  • Children > 28d - adult

Team behind Neonatal in-hospital cause of death determination by minimal invasive tissue sampling technique in a low-income region of Argentina

Neonatal in-hospital cause of death determination by minimal invasive tissue sampling technique in a low-income region of Argentina.

  • Mauricio T. Caballero
  • FundaciĆ³n INFANT
  • Argentina
Objectives
  • To determine the burden of asphyxia and respiratory and central nervous system infectious diseases as COD in neonates hospitalized in our hospital Network.
  • To identify demographic and clinical factors associated with neonatal in-hospital deaths.
  • To explore family and physician acceptance of MITS as a routine procedure after in-hospital neonatal death
Target Population
  • Neonates

ZPRIME Team

Using MITS to calibrate adjudicated respiratory vs. non-respiratory deaths among young Zambian infants

  • Christopher Gill
  • University Teaching Hospital
  • Zambia
Objectives
  • To assess the feasibility and acceptability of MITS sampling in this population
  • To use MITS to calibrate our existing process for adjudicating infant deaths as 'Respiratory' vs. 'Non-Respiratory'
  • To use MITS to establish the rate of PCR concordance between upper and lower respiratory tract RSV infections
Target Population
  • Infants 4d - 6m